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Placebo will be dispensed in 1 month supply, so that compliance can be reconciled at monthly follow-up visits, and recorded in accountability logs. Analysis of systemic and airway inflammation in obstructive sleep apnea. Treatments will be assigned at random (like flipping a coin), and participants will not be aware of which treatment they receive. There is a 2/3 chance that participants will receive dimethyl fumarate. Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions. Once the otolaryngologist determines that CPAP is the right treatment, CPAP should be used on a nightly basis. CPAP is an effective means of treating sleep apnea and snoring.
It keeps airway passages open which prevents pauses in breathing and helps patients get better sleep. Some patients complain of mask discomfort, nasal congestion, and nose and throat dryness when using CPAP.
The primary treatment for OSA, known as Continuous Positive Airway Pressure (CPAP), is delivered by a mechanical device and mask that blows air into the airway to keep it open during sleep.
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